Researchers who have attempted to collect and compare bilateral labor agreements have encountered varying degrees of accessibility of information on these agreements. Why is it harder to find out information on some bilateral labor agreements than others? In this Article, we argue that it is more difficult to find information and agreements tend to be more informal when governments want to obscure what they are doing. Building on insights from the study of optimal obfuscation in trade policy and research on (...) informal institutions in international politics, we argue that policymakers use more informal agreements and make it more difficult to find information on BLAs when they think they will be politically unpopular and are unlikely to be ratified. In contrast, leaders will be more likely to use formal agreements when they want to lock in a policy. Drawing on original quantitative data on the accessibility of information on bilateral labor agreements and Peters’ 2019 database on BLAs, the Article analyzes the accessibility of information on bilateral labor agreements and finds some support for our argument. (shrink)

Do our lives have meaning? Should we create more people? Is death bad? Should we commit suicide? Would it be better if we were immortal? Should we be optimistic or pessimistic? Life, Death, and Meaning brings together key readings, primarily by English-speaking philosophers, on such 'big questions.'.

Anti-selection occurs when information asymmetry exists between insurers and applicants. When an applicant knows they are at high risk of loss, but the insurer does not, the applicant may try to use this knowledge differential to secure insurance at a lower premium that does not match risk.

Disturbances of consciousness, including fluctuations in attention and awareness, are a common and clinically important symptom in dementia with Lewy bodies. In the present study we investigate potential mechanisms of such disturbances of consciousness in a clinicopathological study evaluating specific components of the cholinergic system. [3H]Epibatidine binding to the high-affinity nicotinic receptor in the temporal cortex differentiated DLB cases with and without DOC, being 62–66% higher in those with DOC. The were no differences between DLB patients with or without DOC (...) in 125I-labeled α-bungaratoxin binding to the low-affinity nicotinic receptor, [3H]pirenzepine binding to the muscarinic M1 receptor, or in choline acetyltransferase activity. These findings provide support for the hypothesis that cholinergic activity is an important neural correlate if consciousness and suggest a mechanism of DOC in DLB involving alterations in the nicotinic receptor, composed of predominantly α4 and β2 subunits. (shrink)

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

When analyzing food systems challenges, considering multiple different narratives might lead to solutions that are more innovative and grounded in the local context relative to considering just a single narrative. However, the relationship between narrative diversity and innovation in food systems is not fully understood. Understanding the structure of and interactions between different food systems narratives can help researchers to identify opportunities (e.g., policies, interventions, and institutions) that could facilitate food systems transformations. This paper explores how narratives about food systems (...) converge and vary between different groups of actors in rural Colombia as well as the implications for the co-development of innovative solutions amongst these actors to address food system challenges. As a case study, we focus on an important national policy initiative in Colombia, A Ciencia Cierta, which connects public science and civil society to implement community-based innovations. We conducted 47 interviews with key stakeholders, including policymakers, facilitators, academics, community leaders, and community participants who had been part of the initiative in Colombia, and experts about narratives in food systems globally. We found that actors (both individuals and groups) possess multiple narratives about food systems which evolve over time and adjust according to varying circumstances. Our findings indicate that hybrid innovations enabled by diverse knowledge(s) provide alternative solutions to overcome challenges faced by actors in food systems. This paper generates theoretical and empirical contributions to the growing study of how epistemic plurality can enhance innovation pathways in food systems. (shrink)

We examine Margaret Cavendish’s ecological views and argue that, in the Appendix to her final published work, Grounds of Natural Philosophy (1668), Cavendish is defending a normative account of the way that humans ought to interact with their environment. On this basis, we argue that Cavendish is committed to a form of what, for the purposes of this paper, we call ‘deep ecology,’ where that is understood as the view that humans ought to treat the rest of nature as (...) something of intrinsic value. The reading of Cavendish we defend in this paper also commits her to a naturalistic account of ‘moral facts’ about how humans ought to interact with their environment. That is, on our reading of Cavendish, ‘moral facts’ (i.e., facts about how we ought and ought not to behave, and what it is right or wrong for us to do) are grounded in facts about nature—and, in Cavendish’s case, its (ir)regularity. Such facts are hypothetical, rather than categorical: they are facts about how we ought to act if we wish to attain happiness or flourishing. We thus contend that Cavendish anticipates, at least loosely speaking, movements in both deep ecology and in naturalistic meta-ethics that came to prominence well after the time in which she was writing. (shrink)

Le glissement de l’attention du langage parlé vers le langage intérieur dans la philosophie médiévale est bien connu. Ce qui n’a jamais été remarqué est le rôle joué par la reconnaissance des paradoxes et problèmes de signification posés par les caractéristiques physiques du langage parlé. Cet essai examine ces paradoxes et les solutions apportées dans les écrits de Pierre Abélard, de ses contemporains, et de quelques auteurs du début du xiii e siècle.

Cottingham aims to present Descartes' philosophy in a way that makes "the issues reasonably accessible to students who may be approaching the Cartesian system for the first time". He also aims to do "justice to the complexities of argument involved". There is a potential conflict here: making the issues accessible can lead one to oversimplify them; capturing the complexities of Descartes' thought can cause one to leave inexperienced readers behind. When the conflict arises, Cottingham routinely picks accessibility over philosophical complexity. (...) As a result, his book is not as philosophically sophisticated as other commentaries, such as E. M. Curley's, Margaret Wilson's and Bernard Williams's, but it is a superb introduction to Descartes' philosophy for the uninitiated. Cottingham places Descartes' philosophical ideas within the context of the intellectual climate of his time and shows the interrelations between major elements of Descartes' system, from his epistemology to his view of the physical universe to his physiological and psychological theories. The book's only drawback as an introduction is its limited bibliography. Many who read this book will be inspired to learn more; a more extensive, perhaps topically organized, bibliography would have helped them get started. (shrink)

Based on talks provided under the title "The Christian religion & its philosophy".

As medical science continues its rapid advances, questions are raised that have more to do with theology than with technology: Where is God when I am hurt or suffering? What role does God play in my healing? "Pain Seeking Understanding" examines how believers and nonbelievers alike wrestle with questions of faith when confronted with pain and suffering that medicine alone cannot treat. Margaret Mohrmann and Mark Hanson call upon fellow experts in the fields of medicine, ethics, theology, and pastoral (...) care to help them weave the complex story of faith and science working together to ease suffering -- and to help broaden our understanding of God's role in suffering and healing. (shrink)

This study investigates how reality television viewing is linked to Facebook. Utilizing a survey of 736 students in a school of journalism at a large Midwestern university, researchers examined whether viewers of different genres of reality television were more prone to problematic information sharing on Facebook. The study found that all viewers of reality were prone to problematic information sharing. However, viewers of drama-, competition-, and crime-based shows were most likely to share problematic information. These results are interpreted using social (...) cognitive theory. (shrink)

This review both praises Richard Miller's book--a thoughtful, judicious, and comprehensive analysis of bioethics for the pediatric age group, notably the first effort worthy of the name--and points out the work still to be done in this area, work firmly based in and illuminated by Miller's ground-breaking thesis. Specifically, the book rightly compels us to recognize obligations of beneficence as primary and to refocus on the child's basic interests, rather than putative "best" interests. There remains much to be done in (...) defining and discerning basic interests and in distinguishing whose interests are on the table when decisions are being made for seriously ill and dying children. (shrink)

Insight has been investigated under the assumption that participants solve insight problems with insight processes and/or experiences. A recent trend has involved presenting participants with the solution and analysing the resultant experience as if insight has taken place. We examined self-reports of the aha experience, a defining aspect of insight, before and after feedback, along with additional affective components of insight (e.g., pleasure, surprise, impasse). Classic insight problems, compound remote associates, and non-insight problems were randomly interleaved and presented to participants. (...) Solution feedback increased ratings of aha experience in both insight and non-insight problems, with this result being driven by responses to solutions that were initially incorrectly generated. Ratings of aha for correctly generated solutions decreased after the correct solution was presented. These findings have implications for insight research paradigms as well as informing teaching methods. (shrink)

In this profoundly theological reflection on illness, healing, and the doctor-patient relationship, pediatrician Margaret Mohrmann bridges the sometimes disparate worlds of medicine and faith, of high technology and ultimate concern. Drawing on her two decades of experience treating children who suffer from disease and dysfunction, Mohrmann movingly reveals the temptations of idolatry that beset our understanding of health and life, the intrinsic connectedness underlying all medical encounters, and the difficulties and riches of using scripture as a moral resource. In (...) clear, accessible language Mohrmann emphasizes the importance of interpreting the lives of the suffering as meaningful and ongoing stories - stories that require all of us to respond in healing ways. Uncovering insights from such diverse sources as the apostle Paul, Alasdair MacIntyre and Flannery O'Connor, she suggests that what is required for a truly human life is not the absence of pain, but the presence of others. Both pastoral and prophetic, Medicine as Ministry is a challenge to rethink the purposes of health care - and to better discern the human condition. (shrink)

This paper is about a drug called misoprostol and its controversial clinical and social lives. Although originally developed as a prevention for gastric ulcers, in the 1980s, it developed an off-label reputation as an abortifacient. The drug’s association with clandestine abortion has profoundly shaped its social life as a marginal and suspect character in the realm of global maternal and reproductive health where it has the potential to prevent two major causes of maternal death––postpartum hemorrhage and unsafe abortion. The social (...) life of misoprostol has also been shaped by the question of authoritative practice, that is, the question of who can deliver medicine. Both issues are about the specters of misuse of misoprostol: off-label, illegal, immoral, or by unlicensed providers. In this paper, I focus ethnographically on two women’s health nongovernmental organizations that have been conducting clinical testing and advocacy for the use of misoprostol for reproductive indications in global maternal health settings. Drawing on the notions of pharmaceutical activism and protocol feminism, I describe and analyze how the tools of evidence and authoritative practice have been reassembled in new networks of expertise toward the social justice goals of life, access, and dignity for women. (shrink)

The ancient scholia and various modern editors interpret these lines as a description of the prodigies which followed the death of Caesar. It is bold to criticize a view so widely held, but its acceptance, to me, involves considerable difficulties. The first is the long interval between Caesar's death and the date of the Ode. About this date editors vary, but the general view is that it belongs either to the year 29 or 28 B.C.

The ability to generate diverse ideas is valuable in solving creative problems ; yet, however advantageous, this ability is insufficient to solve the problem alone and requires the ability to logically deduce an assessment of correctness of each solution. Positive schizotypy may help isolate the aspects of divergent thinking prevalent in insight problem solving. Participants were presented with a measure of schizotypy, divergent and convergent thinking tasks, insight problems, and non-insight problems. We found no evidence for a relationship between schizotypy (...) and insight problem solving. Relationships between divergent thinking and insight problem solving were also surprisingly weak; however, measures of convergent thinking had a stronger relationship with problem solving. These results suggest that convergent thinking is more important than divergent thinking in problem solving. (shrink)

In the first chapter, Erskine provides an interesting and exhaustive analysis of the evidence for Zeno's Politeia. He rejects statements to the effect that Zeno wrote the Politeia in his early days when he was influenced by the Cynics as the invention of the Stoics of the first century B. C., who were embarrassed by its contents. Two of the stipulations in the Politeia, that there should be no coinage and no private property, he explains in terms of the economic (...) and political instability in fourth-century Greece. He argues that "the ideal society of Zeno's Politeia contained only the wise". There is no reason to suppose, however, that this society, however ideal, could ensure that every child would become wise. The most it could claim was that every child would become an adult who was making progress towards virtue. I can see no reason why the presence of those actively seeking virtue would disturb the homonoia of the ideal city. (shrink)

In this article, I respond to important questions raised by Gallagher and Jacobson in the field of cognitive science about face-to-face interactions in Heidegger’s account of ‘intersubjectivity’ in Being and Time. They have criticized his account for a lack of attention to primary intersubjectivity, or immediate, face-to-face interactions; he favours, they argue, embodied interactions via objects. I argue that the same assumption underlies their argument as did earlier critiques of a lack of an account of the body in Heidegger ; (...) namely that because the body is not explicitly discussed in Being and Time, embodiment, rather than stressing the immediacy of experience, is insufficiently acknowledged in his emphasis on ‘being-in-the-world’. Through placing Gallagher and Jacobson’s accounts of intersubjectivity and the body alongside Heidegger’s accounts of Mitsein and Leib, this article shows Heidegger’s radical position on the body as immersed in a holistic environment, and its reverberations on his account of intersubjectivity. I argue that Dasein’s embodied engagement in the world is always one of immediacy and that the body of the other is perceived as ‘tied into’ its context, as well. In so doing, I offer an Heideggerian account of ecstatic involvement which moves away from the distinction between primary and secondary intersubjectivity toward an immediate engagement with objects and people always already ‘tied into’ a context; an account that, through the concept of Fürsorge, includes shifts of attention between objects and people that allow for the ethical distinctions Gallagher and Jacobson are looking for. (shrink)

Studies of participatory governance generally examine the input and/or output side of policy processes. Often neglected is the throughput: Does the state have the political and technical capacity to implement the decisions that deliberative bodies make? In this study of Brazilian river-basin committees, the authors find that activists inside and outside the state often must collaborate to overcome resistance to change and provide state officials with resources they lack. They argue that this does not constitute the transfer of state responsibility (...) to private actors but rather the mobilization of a state's capacity to defend the public interest. (shrink)

In this article, I argue that Donna Haraway's figure of the cyborg needs to be reassessed and extricated from the many misunderstandings that surround it. First, I suggest that we consider her cyborg as an ethical concept. I propose that her cyborg can be productively placed within the ethical framework developed by Luce Irigaray, especially in relationship to her concept of the “interval between.” Second, I consider how Haraway's “cyborg writing” can be understood as embodied ethical writing, that is, as (...) a contemporary écriture feminine. I believe that this cyborgian “writing the body” offers us a way of both creating and understanding texts that think through ethics, bodies, aesthetics, and politics together as part of a vital and relevant contemporary feminist ethics of embodiment. I employ the term “poethics” as a useful way to describe such a practice. (shrink)

Several studies have indicated that scientists are likely to have an outlook on both facts and values that are different to that of lay people in important ways. This is one significant reason it is currently believed that in order for scientists to exercise a reliable ethical reflection about their research it is necessary for them to engage in dialogue with other stakeholders. This paper reports on an exercise to encourage a group of scientists to reflect on ethical issues without (...) the presence of external stakeholders. It reports on the use of a reflection process with scientists working in the area of animal disease genomics (mainly drawn from the EADGENE EC Network of Excellence). This reflection process was facilitated by using an ethical engagement framework, a modified version of the Ethical Matrix. As judged by two criteria, a qualitative assessment of the outcomes and the participants’ own assessment of the process, this independent reflective exercise was deemed to be successful. The discussions demonstrated a high level of complexity and depth, with participants demonstrating a clear perception of uncertainties and the context in which their research operates. Reflection on stakeholder views and values appeared to be embedded within the discussions. The finding from this exercise seems to indicate that even without the involvement of the wider stakeholder community, valuable reflection and worthwhile discourse can be generated from ethical reflection processes involving only scienitific project partners. Hence, the previous assumption that direct stakeholder engagement is necessary for ethical reflection does not appear to hold true in all cases; however, other reasons for involving a broad group of stakeholders relating to governance and social accountability of science remain. (shrink)

THE OBJECT OF THIS ESSAY IS TO EXPLORE PRIOR CHRISTIAN CONCEPTIONS of integrity to clarify and deepen current understanding of the term, by demonstrating its evolution and bringing forward nuances of meaning that may be overlooked or deemphasized. In doing so, I hope to contribute to a broader discussion of the place of integrity in present-day Christian ethics.

The aim of the present paper is to describe three different attempts, which have been made by philosophers, to define what quality of life is; and to spell out some of the difficulties that faces each definition. One, Perfectionism, focuses on the capacities that human beings possess: capacities for friendship, knowledge and creative activity, for instance. It says that the good life consists in the development and use of these capacities. Another account, the Preference Theory, urges that satisfying one's preferences, (...) or desires, is what improves one's quality of life. And a third account, Hedonism, sees life-quality as consisting in the enjoyment of pleasure and the avoidance of pain. The paper describes and evaluates objections to each of these views, thereby displaying their weaknesses and strengths. Since no view comes out as the right one there is a choice to be made. At the end of the paper it is being discussed how well each of the views cohere with different methodologies used in quality of life research. Also it is suggested that considerations about what the research is to be used for are relevant. (shrink)